冯江华

发布时间:2016-07-29浏览次数:10

个人简介:

冯江华,博士,教授,博士生导师


教育背景:

学士:山西大学,1993-1997

博士:中国科学院长春应用化学研究所,1997-2002


工作经历:

博士后:法国国家科研中心(CNRS)格勒诺布尔生物结构研究所,

        2003.2.-2003.9.;英国曼彻斯特大学,2003.10.-2005.9.

副研究员:中国科学院武汉物理与数学研究所,2005.12.-2011.1.

副教授:厦门大学电子科学系 2011.2.-2012.7.

教授:厦门大学电子科学系 2012.8.-现在


Journal of Proteomics, Journal of Nanoparticle Research, Micro & Nano Letters, Molecular

BioSystems, 波谱学杂志、分析化学等期刊的独立审稿专家。


联系方式:

Email:jianghua.feng@xmu.edu.cn        Tel: 86-592-2183301        Fax: 86-592-2189426


研究方向:

◆医用纳米材料的性能研究和生物安全性评价

◆代谢组学技术在毒理、病理和药理方面的应用研究

◆食品安全和质量控制


学科专长:

核磁共振、代谢组学、磁共振成像


Profile:

Jianghua Feng, Ph. D., Professor

Educational Background:

B. S. (1993-1997): Shanxi University

Ph. D. (1997-2002): 

Changchun Institute of Applied Chemistry, Chinese Academy of Sciences

Appointments:

2003.2-2003.9: Postdoctoral Research Associate, Laboratoire de RMN, Institut de Biologie Structurale - J.-P. Ebel, Grenoble, France

2003.9-2005.9: Postdoctoral Research Associate, Faculty of Life Sciences, The University of Manchester, Manchester, UK

2005.12-2011.1: Associate Professor, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences

2011.2.-2012.7.: Associate Professor, Department of Electronic Science, Xiamen University

2012.8.-present: Professor, Department of Electronic Science, Xiamen University

Peer Review Activities (Journal Reviewership):

Reviewer for Journal of Proteomics, Journal of Nanoparticle Research, Micro & Nano Letters, Molecular BioSystems and Chinese Journal of Magnetic Resonance,Chinese Journal of Analytical Chemistry

Research Interests:  The evaluations of efficacy and bio-safety studies of nanomaterials in biomedicine; NMR-based metabonomics and its applications in toxicology, pharmacology and pathology; Food safety and quality control

Research Speciality: NMR, metabonomics, and MRI


科研项目

 福建省科技计划重点项目:快速检测和鉴别地沟油的核磁共振技术发展和谱仪小型化设计,2014.9.-2017.6.

 国家卫生和计划生育委员会科研基金:核磁共振代谢组学技术用于胰腺癌的早期诊断,2013.10.-2016.9.

 国家自然科学基金:基于核磁共振的代谢组学技术发现胰腺癌的生物标志物及早期诊断的应用,2013.1.-2016.12.


代表性论文

 Zhishui Li, Chenghong Lin, Jingjing Xu, Huifeng Wu, Jianghua Feng*, Heguang Huang. The relations between metabolic variations and genetic evolution of different species. Analytical Biochemistry, 2015, in press, DOI: 10.1016/j.ab.2015.02.024.

 Jianghua Feng*, Youe Yan, Gai Liang, Yansong Liu, Xiaojun Li, Benjian Zhang, Liaobin Chen, Hong Yu, Xiaohua He, Hui Wang. Maternal and fetal metabonomic alterations in prenatal nicotine exposure-induced rat intrauterine growth retardation. Molecular and Cellular Endocrinology, 2014, 394: 59-69.

 Jinquan Li, Zijian Zhou, Jianghua Feng*, Shuhui Cai, Jinhao Gao, Zhong Chen. NMR-based metabonomic analysis of MnO-embedded iron oxide nanoparticles as potential dual-modal contrast agents. Journal of Nanoparticle Research, 2014, 16: 2411-2426.

 Hao Kou, Yansong Liu, Gai Liang, Jing Huang, Jieqiong Hu, You-e Yan, Xiaojun Li, Hong Yu, Xiaohua He, Baifang Zhang, Yuanzhen Zhang, Jianghua Feng*, Hui Wang. Maternal glucocorticoid elevation and associated blood metabonome changes might be involved in metabolic programming of intrauterine growth retardation in rats exposed to caffeine prenatally. Toxicology and Applied Pharmacology, 2014, 275: 79-87.

 Jianghua Feng*, Jinquan Li, Huifeng Wu, Zhong Chen. Metabolic response of HeLa cells to silica nanoparticles by NMR-based metabolomic analyses. Metabolomics, 2013, 9: 874-886.

 Jinquan Li, Zhenghuan Zhao, Jianghua Feng*, Jinhao Gao, Zhong Chen. Understanding the metabolic fate and assessing the biosafety of MnO nanoparticles by metabonomic analysis. Nanotechnology, 2013, 24: 455102.

 Chenhong Lin, Shuhui Cai, Jianghua Feng*. Positive contrast imaging of SPIO nanoparticles. Journal of Nanomaterials, 2012, Article ID 734842, 9 pages. DOI: 10.1155/2012/734842.

 Yansong Liu, Dan Xu, Jianghua Feng*, Hao Kou, Gai Liang, Hong Yu, Xiaohua He, Baifang Zhang, Liaobin Chen, Jacques Magdalou, Hui Wang. Fetal rat metabonome alteration by prenatal caffeine ingestion probably due to the increased circulatory glucocorticoid level and altered peripheral glucose and lipid metabolic pathways. Toxicology and Applied Pharmacology, 2012, 262: 205-216.

 J. H. Feng*, H. L. Liu, K. Bhakoo, L. H. Lu, Z. Chen. “A Metabonomic Analysis of Organ Specific Response to USPIO Administration”. Biomaterials, 2011, 32: 6558-6569.

 J. H. Feng, J. Zhao, K. Bhakoo, F. H. Hao, C. Chen, H. R. Tang. “NMR-based Metabonomic Analyses of the Effects of Ultrasmall Superparamagnetic Particles of Iron Oxide (USPIO) on Macrophage Metabolism”. J. Nanopart. Res., 2011, 13: 2049-2062.

 J. H. Feng*, M. M. Meloni, S. M. Allan, S. Faulkner, J. Nvrvainen, R. Vidyasagar, R. Kauppinen. “Tuftsin Derivatives of FITC, Tb-DOTA or Gd-DOTA as Potential Macrophage-Specific Imaging Biomarkers”. Contrast Media & Mol. Imaging., 2010, 5: 223-230.

 G. Zhang, J. H. Feng*, L. H. Lu, B. H. Zhang, X. M. Zhao, L. Y. Cao. “Fluorescent magnetic nanoprobes: Design and application for cell imaging’’. J. Colloid. Interf. Sci., 2010, 351: 128-133.

 J. H. Feng*, H. L. Liu, L. M. Zhang, K. Bhakoo, L. H. Lu. ‘‘An Insight into the Metabolic Responses of Ultra-small Superparamagnetic Particles of Iron Oxide using Metabonomic Analysis of Biofluids’’. Nanotechnology, 2010, 21: 395101.

 T. Koullourou, L. S. Natrajan, H. Bhavsar, S. J. A. Pope, J. H. Feng, J. Narvainen, R. Shaw, E. Scales, R. Kauppinen, A. M. Kenwright, and S. Faulkner. “Synthesis and spectroscopic properties of a prototype single molecule dual imaging agent comprising a heterobimetallic rhenium-gadolinium complex”. J. Am. Chem. Soc., 2008, 130: 2178-1279.

 A. Denes, R. Vidyasagar, J. H. Feng, J. Narvainen, B. W. McColl, R. A. Kauppinen, and S. M. Allan. “Proliferating resident microglia after focal cerebral ischaemia in mice”. J. Cereb. Blood Flow. Metab., 2007, 27: 1941-1953.

 8.ZnS/CdSe/ZnS nanocrystals-tetrapeptide biolabeling agent”. J. Nanosci. Nanotechnol., 2007, 7: 2301-2308.

 R. J. Aarons, J. Notta, M. M. Meloni, J. H. Feng, J. Narvainen, S. Allan, N. Spencer, R. A. Kauppinen, J. S. Snaith, and S. Faulkner. “A luminescent probe containing a tuftsin targeting vector coupled to a terbium complex”. Chem.Comm., 2006, 1: 909-911.

 H. F. Wu, X. J. Li, J. H. Feng, W. S. Li, Z. F. Li, P. Q. Liao, Y. J. Wu, and F. K. Pei. “Comparison of Biochemical Effects Induced by Changle between Male and Female Rats Using NMR and ICP-MS Techniques”. J. Rare Earth., 2006, 24: 108-114.

 G. Y. Sun, J. H. Feng, H. F. Wu, F. K. Pei, K. Fang, H. Lei. ‘‘Investigation of Sandwiched Gadolinium (III) Complexes with Tungstosilicates as Potential MRI Contrast Agents’’. Magn. Reson. Imaging, 2004, 22: 421-426.

 H. F. Wu, X. Y. Zhao, J. H. Feng, G. Y. Sun, Y. J. Wu, F. K. Pei, Y. X. Nie. “NMR and Pattern Recognition Stuides on the Acute Biochemical Effects of Lu(NO3)3”. Chin. J. Chem., 2004, 22: 849-853.

 J. H. Feng, G. Y. Sun, F. K. Pei, M. L. Liu. “Comparison between Gd-DTPA and Several Bisamide Derivatives as Potential MRI Contrast Agent”. Bioorgan. Med. Chem., 2003, 11 (15): 3359-3366.

 J. H. Feng, X. J. Li, F. K. Pei, Y. X. Nie. “Bioeffects Evaluation of a Long-Term Administering Changle by Proton NMR Method and Biochemical Examination”. Chin. J. Chem., 2003, 21: 320-326.

 G. Y. Sun, J. H. Feng, F. Y. Jing, F. K. Pei, M. L. Liu. “Synthesis and Evaluation of Novel Polysaccharide-Gd-DTPA Compounds as Contrast Agent for MRI”. J. Magnetism Magn. Materials, 2003, 265 (2): 123-129.

 J. H. Feng, X. J. Li, F. K. Pei, X. Chen, S. L. Li, Y. X. Nie. “1H NMR Analysis for Metabolites in Serum and Urine from Rats Administrated Chronically with La(NO3)3”. Anal. Biochem., 2002, 301: 1-7.

 J. H. Feng, X. J. Li, F. K. Pei, G. Y. Sun, X. Zhang, M. L. Liu. “An Evaluation of the Lanthanide Polyoxometalates as Possible MRI Contrast Agent”. Magn. Reson. Imaging., 2002, 20: 407-412.

 J. H. Feng, G. Y. Sun, F. K. Pei, M. L. Liu. “Comparison between GdDTPA and Two Gadolinium Polyoxometalates as Potential MRI Contrast Agents”. J. Inorg. Biochem., 2002, 92 (3-4): 193-199.

 G. Y. Sun, J. H. Feng, F. Y. Jing, F. K. Pei. “Arabinogalactan as a Carrier for Contrast Agent in Magnetic Resonance Imaging”. Chem. J. Chin. Univ., 2002, 23 (10): 1837-1841.

 J. H. Feng, X. J. Li, X. Y. Li, F. K. Pei. “ Solution Structures of Lanthanide(Ⅲ) Complexes of DTPA-BIN: A One-Dimensional and Two-Dimensional NMR Analysis”. Chem. J. Chin. Univ., 2001, 22 (10): 1615-1619.